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  Patents

  1. F. Wattimena and R.A. Sheldon Oxiranes Ger. Offen., 2,333,315 (1974) (C.A., 80, p95699y, 1974). DE 2334315, 24-01-1974, Shell, The Netherlands

  2. R.A. Sheldon, J.W. van der Meer and A.J. Mulder 3-Phenoxybenzaldehyde, substituted if desired Ger. Offen., 2,624,360 (1976) to Shell; CA, 86, 120984w (1977). DE 2624360, 16-12-1976, Shell, The Netherlands

  3. R.A. Sheldon, J.W. van der Meer, A.J. Mulder, P.A. Verbrugge, H. Verbrugge and E.A. Ginsberg 3-Bromobenzaldehyde Ger. Offen., 2,624,410 (1976) to Shell; CA, 86, 120985x (1977). DE 2624410, 16-12-1976, Shell, The Netherlands

  4. H.P. Rosinger, D.A. Wood and R.A. Sheldon m-Aryloxbenzaldehydes Ger. Offen., 2,704,512 (1977) to Shell; CA, 87P, P 167731x. DE 2704512, 11-08-1977, Shell, The Netherlands CA 1195695, 22-10-1985, Shell, Canada

  5. R.A. Sheldon, P. Been, D.A. Wood and R.F. Mason Benzyl esters with pesticidal action Ger. Offen., 2,708,590 (1977) to Shell; CA, 88, 6563z (1978). DE 2708590, 15-09-1977, Shell, The Netherlands

  6. R.A. Sheldon and R. van Helden Mixture of m-aryloxybenzyl chloride and m-aryloxybenzal chloride Ger. Offen., 2,744,603 (1978) to Shell; CA, 89, 42758w (1978). DE 2744603, 13-04-1978, Shell, The Netherlands

  7. R.A. Sheldon, M. Anderson, H. Verbrugge and J.L.M. Syrier 2-Cyanohexanoic acid derivatives Eur. Pat. Appl. 3,857 (1979); CA, 92, 41374t (1980). EP 3857, 05-09-1979, Shell, The Netherlands

  8. A. Reinink and R.A. Sheldon a-Cyanobenzyl esters Braz. Pat., 7806,364 (1979) to Shell; CA, 92, 7613p. BR 7806364, 24-04-1979, Shell, The Netherlands

  9. M.J. van den Brink and R.A. Sheldon Cyclopropanecarboxylic acid esters DE 2736258, 22-02-1979, Shell, The Netherlands US 4096170, 20-06-1978, Shell, USA

  10. R.A. Sheldon Oxabicycloheptane derivative intermediates for pyrethroid insecticides Brit. Pat. Appl. 2,025,966 (1980) to Shell; CA, 93, 186167h (1980). GB 2025966, 30-01-1980/13-10-1982, Shell, The Netherlands

  11. R.A. Sheldon and J.H. Wevers Process for the preparation of cyclobutanone derivatives Brit. Pat., 1,589,518 (1981) to Shell; CA, 95, 150044t (1981). GB 1589518, 13-05-1981, Shell, The Netherlands

  12. M.J. van der Brink and R.A Sheldon Cyanomethyl esters of cyclopropanecarboxylic acids Can. Pat., 1,122,609 (1982) to Shell; CA, 97, 127130a (1982). CA 1122609, 27-04-1982, Shell, Canada

  13. R.A. Sheldon and H.J. Heijmen Pivaloylacetic acid esters Brit. Pat. Appl., 2,088,354, (1982) to Shell; CA, 97, 162390g (1982). GB 2088354, 09-06-1982, Shell, The Netherlands US 4656309, 07-04-1987, idem

  14. A.J.C. van Seters, R.A. Sheldon and E.W. Uurbanus A chloropropyl compound Brit. Pat. Appl., 2,108,953 (1983) to Shell; CA, 99, 189310p (1983). GB 2108953, 25-05-1993, Shell, The Netherlands

  15. J. Dakka and R.A. Sheldon Werkwijze voor de bereiding van een p-hydroxybenzaldehyde Preparation of p-hydroxybenzaldehydes NL 9200968, 03-01-1994, DSM, The Netherlands.

  16. R.A. Sheldon, J.D. Chen and J. Dakka Werkwijze voor de gekatalyseerde ontleding van organische hydroperoxiden The catalyzed decomposition of organic hydroperoxides WO 9408932, 28-04-1994, TU Delft

  17. R.A. Sheldon, J.D. Chen, J. Dakka Method for the catalyzed autoxidation of (cyclo)alkanes, (cyclo)alkyl aromatics and alcohols derived therefrom WO 9417021, 04-08-1994, TU Delft, The Netherlands

  18. M.C. de Zoete, F. van Rantwijk and R.A. Sheldon A process for carrying out enzymatically catalyzed conversions of organic compounds WO 9507359, 16-03-1995, TU Delft, The Netherlands

  19. K.G. Davenport, R.A. Sheldon, J. le Bars and W.H. Müller Process for prepation of 4-hydroxyacetophenone oxime US 5466869, 14-11-1995, Hoechst Celanese, USA WO 9613480, 09-05-1996, idem

  20. R.A. Sheldon, L. Maat and G. Papadogianakis Preparation of arylacetic and arylpropionic acids US 5536874, 16-07-1996, Hoechst Celanese, USA WO 9626177, 29-08-1996, idem

  21. R.A. Sheldon, J.D. Chen and J. Dakka Method for the catalyzed decomposition of organic hydroperoxides US Pat. Appl. 08/416,674

  22. J. Dakka, R.A. Sheldon and W.R. Sanderson Heterogeneous transition metal compound oxidation catalysts UK Patent 9602203.3, ingediend 3-2-1996 GB 2309655, 06-08-1997

  23. G.A. Verspui, G. Papadogianakis and R.A. Sheldon Werkwijze voor het bereiden van een polyketon in een waterig medium NL 1007422, 1999.

  24. A. Dijksman, I.W.C.E. Arends en R.A. Sheldon Werkwijze voor het oxyderen van een alcohol NL 43665, 10-7-1998 , TU Delft. Method and free-radical catalysts for oxidizing alcohols into aldehydes or ketones WO 2000002837, 20-01-2000, TU Delft, The Netherlands

  25. L.M. van Langen, F. van Rantwijk, R.A. Sheldon, H. Slijkhuis, E. de Vroom Process for the acylation of ß-lactam compounds EP 2915P, ingediend 15-12-1998, Gist brocades

  26. R.A. Sheldon, F. van Rantwijk and M. Bakker Aminoacylases for acylation of alcohols and amines EP 99118844.2, ingediend 24-9-1999, Degussa/TU Delft

  27. L. Cao, M.H.J. Janssen, L.M. van Langen and R.A. Sheldon Crosslinked enzyme aggregates EP 99203117.9, ingediend 23-9-1999

  28. D.T. Guranda, A. Khimiouk, L.M. van Langen, F. van Rantwijk and R.A. Sheldon Process for the preparation of optically active amines NL 1016127, ingediend 8-9-2000

  29. D.T. Guranda, L.M. van Langen, F. van Rantwijk. R.A. Sheldon and V.K. Svedas Process for the preparation of optically active amines NL 1016126, ingediend 8-9-2000 NL 1016785, ingediend 4-12-2000

  30. M. Bakker, F. van Rantwijk and R.A. Sheldon Aminoacylases for acylation of alcohols and amines EP 99118844, date of filing 18-8-2000, Degussa-Hüls, Germany EP 1087018, 28-03-2001, idem

  31. A. Kühnle, M. Duda, R.A. Sheldon, S. Manickam, I.W.C.E. Arends, T. Schiffer, G. Fries, J. Kirchhoff and C. Jost Verfahren zur Oxidation von Kohlenwasserstoffen DE 50102926D, 26-8-2004, Creavis, Germany

  32. X. Baucherel and R.A. Sheldon Catalytic oxidation process WO 2002100810, 19-12-2002, ICI, UK

  33. A. Kühnle, C. Jost, R.A. Sheldon, S.M. Chatel, I.W.E. Arends Procedure for the catalytic oxidative cleavage/fission of cyclic saturated and unsaturated compounds DE 10129117, 19-12-2002, Creavis, Germany WO 2002102742, 27-12-2002, Creavis, Germany

  34. P. Lopez-Serrano, L. Cao, F. van Rantwijk and R.A. Sheldon Preparation of cross-linked aggregates of lipases and other enzymes using crown ethers and surfactants WO 2002061067, 08-08-2002, TU Delft, The Netherlands Werkwijze voor het maken van vernette enzymaggregaten NL 1017258, verleend 2 aug. 2002, to Delft University of Technology

  35. S.W. Ramer, G. Huisman, J. Millis, R. Sheldon, S. Del Cardayre, T. Stephen, M. Tobin, A. Cox and S. Christopher Davis Enantioselective production of amino carboxylic acids WO 2002029079, 11-04-2002, Maxygen, USA

  36. V.K. Svedas, D.T. Guranda, A.I. Khimiouk, R.A. Sheldon, F. van Rantwijk and L.M. van Langen Process for the preparation of enantiomerically enriched amines WO 2002020821, 14-03-2002/08-08-2002, DSM, The Netherlands

  37. V.K. Svedas, D.T. Guranda, T. Dorel, R.A. Sheldon, F. van Rantwijk and L.M. van Langen Method for the preparation of enantiomerically enriched amines WO 2002020820, 14-03-2002, DSM, The Netherlands

  38. A. Kühnle, M. Duda, U. Tanger, R.A. Sheldon, I.W.C.E. Arends and M. Sasidharan Method for producing aromatic alcohols, especially phenol WO 2001074767, 11-10-2001, Creavis, Germany

  39. A. Kühnle, M. Duda, R.A. Sheldon, M. Sasidharan, I.W.C.E. Arends, T. Schiffer, G. Fries and J. Kirchhoff Method for oxidizing hydrocarbons and organic compounds WO 2001074742, 11-10-2001/14-02-2002, Creavis, Germany

  40. A. Kuhnle, J. Carsten, R. A. Sheldon, M. M. Chantel and I. W. C. E. Arends, Epoxidation process and cyclic imide catalysts for the manufacture of ethylbenzene hydroperoxide and its use in the preparation of epoxides from alkenes, WO 2003014074 (2003) to Degussa

  41. L. Cao, L.M. van Langen, M.H.A. Janssen and R.A. Sheldon Preparation and properties of crosslinked aggregates of penicillin acylase and other enzymes EP 1088887, 04-04-2001, DSM, The Netherlands

  42. G. Fries, A. Kühnle, C. Jost, M. Neumann, L. Gonsalvi, I.W.C.E. Arends, R.A. Sheldon Herstellung und Verwendung eines Rutheniumkatalysators für die Oxidation von Kohlenwasserstoffverbindungen DE10163579, published 3-7-2003 (Degussa)

  43. A. Kuhnle, J. Carsten, R. A. Sheldon, M. M. chantel and I. W. C. E. Arends, Preparation of saturated alcohols, ketones, aldehydes and carboxylic acids via the equential catalytic oxidation and reduction of unsaturated hydrocarbons, WO 2003004447 (2003) to Degussa

  44. S.C. Davis, J.H. Grate, D.R. Gray, J.M. Gruber, G.W. Huisman, S.K. Ma, L.M. Newman, R. Sheldon and L.A. Wang Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives WO 2004/015132 A2, published 18-2-2004 (Codexis, U.S.A.)

  45. S. C. Davis, J. H. Grate, D. R. Gray, J. M. Gruber, G. W. Huisman, S. K. Ma, Halohydrin dehalogenases and method for production of 4-cyano-3-hydroxybutyric acid esters and amides, WO 20041028 (2004) to Codexis

  46. M. I. Youshko, V.K. Svedas, R. A. Sheldon and L. M. van Langen, Enzymatic kinetic resolution of protected amino acids, WO 2005001107 (2005)

  47. M. C. Kroon, A. Shariati, L. J. Florusse, C. J. Peters, J. van Spronsen, J. Witkamp, R. A. Sheldon and K. I. Gutowski, A process for carrying out a chemical reaction using ionic liquid and carbon dioxide under pressure, WO 2006088348 (2006) to TUDelft

  48. M. Dakka, S. Miseo, S. L. Leon, J. G. Guadalupe, J. Baumgartner, E. Joseph, M. C. A. Van Vliet and R. A. Sheldon, US pat appl. 2006293544 (2006) to Exxon

  49. Biocatalytic processes for the preparation of substantially stereomerically pure fused bicyclic proline compounds, B. Mijts, S. Muley, J. Liang, L.M. Newman, X. Zhang, J. Lalonde, M. D. Clay, J. Zhu, J. Gruber, J. Colbeck, et al, PCT Int. Appl. (2010), WO 2010008828 A2 20100121.

  50. Production of 2,6-dioxabicyclo-(3.3.0)-octane-4,8-dione by oxidation of dianhydrohexitols or hydroxy ketones,U. Dingerdissen, J. Pfeffer, T. Tacke, T. Haas, H. Schmidt, M. Volland, M. Lettmann, M. Rimbach, R. Sheldon, M. Janssen, PCT Int. Appl. (2010), WO 2010089223 A1 20100812.

  51. Preparation of aldehydes and ketones from primary and secondary alcohols, U. Dingerdissen, J. Pfeffer, T. Tacke, T. Haas, H. Schmidt, F. Klasovsky, R. Sheldon, M. Janssen, M. Volland, M. Rimbach, et al, PCT Int. Appl. (2010), WO 2010089213 A1 20100812.

  52. Non-leachable magnetic cross-linked enzyme aggregate, R. A. Sheldon, M. J. Sorgedrager andB. Kondor, PCT Int. Appl. (2012) WO 2012/023847 A2

  53. N. J. M. C. Penders, P. W. J. Derks, G. F. Versteeg, E. Madore, R. A. Sheldon, N. Voyer, S. Fradette, J. Carley, G. R. Kelly, Enhanced enzymatic CO2 capture techniques according to solution pKa, temperature and/or enzyme character PCT Int. Appl.(2012) WO 2012167388 A1 20121213

  54. Klasovsky, Florian; Haas, Thomas; Tacke, Thomas; Pfeffer, Jan Christoph; Rimbach, Michael; Volland, Michael; Janssen, Michiel; Sheldon, Roger; Haberland, Juergen ,Continuously Operable method for producing carbonyl compounds by means of a catalyst containing a nitroxyl radical, PCT Int. Appl. (2012) WO 2012139666A1 20121018

  55. R. A. Sheldon, M. J. Sorgedrager, S. Van Pelt, A. Weisman, O. Friedman, Preparation of nicotine comprising the enzymatic reduction of 4-(methylamino)-1-(pyridin-3-yl) butan-1-one, PCT Int. Appl. (2014), WO 2014174505 A2 20141030;

  56. S. van Pelt, M. H. A. Janssen, J-A. M. Rasmussen, M. J. Sorgedrager, R. A. Sheldon, P. Koning, Cross-Linked Enzyme Aggregates comprising Magnetizable Particles, (2018) WO2018/004341 A1

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